Hybrid genes over-express pertactin from Bordetella pertussis.

doi:10.1016/0264-410x(94)00015-f

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Article

Hybrid genes over-express pertactin from Bordetella pertussis.

Vaccine - 1 Apr 1995

Loosmore S M, Yacoob R K, Zealey G R, Jackson G E, Yang Y P, Chong P S, Shortreed J M, Coleman D C, Cunningham J D, Gisonni L

Abstract excerpt

Pertactin is a surface adhesin of Bordetella pertussis which is produced in small quantities when expressed from the native prn promoter. Hybrid genes were constructed in which the prn promoter was replaced by either the fha or tox promoter. Recombinant B. pertussis strains containing chromosomally integrated hybrid tox promoter/prn (toxpprn) or fha promoter/prn (fhapprn) genes expressed pertactin at...

Topics

Alleles
Amino Acid Sequence
Animals
Antigens, Bacterial
Bacterial Adhesion
Bacterial Outer Membrane Proteins
Base Sequence
Bordetella pertussis
Cloning, Molecular
DNA, Recombinant
Gene Amplification

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression

Genes, Bacterial

Guinea Pigs

Immunohistochemistry

Mice

Mice, Inbred BALB C

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 7483778
DOI: 10.1016/0264-410x(94)00015-f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7483778-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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