Article
Expression of Interleukin-5– and Granulocyte Macrophage–Colony-Stimulating Factor–Responsive Genes in Blood and Airway Eosinophils
24 Nov 2003
Abstract excerpt
Because interleukin (IL)-5 family cytokines are critical regulators of eosinophil development, recruitment, and activation, this study was initiated to identify proteins induced by these cytokines in eosinophils. Using oligonucleotide microarrays, numerous transcripts were identified as responsive to both IL-5 and granulocyte macrophage-colony-stimulating factor (GM-CSF), but no transcripts were markedly affected...
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