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Article

A stem-loop "kissing" model for the initiation of recombination and the origin of introns.

Molecular biology and evolution - 1 Sept 1995

Forsdyke D R

Abstract excerpt

Mutations which improve the efficiency of recombination should affect either the proteins which mediate recombination or their substrate, DNA itself. The former mutations would be localized to a few sites. The latter would be dispersed. Studies of hybridization between RNA molecules have suggested that recombination may be initiated by a homology search involving the "kissing" of the tips of stem loops. This...

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PMID: 7476142
DOI: 10.1093/oxfordjournals.molbev.a040273

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