Article
Intrahost human immunodeficiency virus type 1 evolution is related to length of the immunocompetent period.
Journal of virology - 1 Nov 1995
Lukashov V V, Kuiken C L, Goudsmit J
Abstract excerpt
The antigenic diversity threshold theory predicts that antigenic sites of human immunodeficiency virus type 1, such as the V3 region of the external glycoprotein gp120, evolve more rapidly during the symptom-free period in individuals progressing to AIDS than in those who remain asymptomatic for...
Topics
- Acquired Immunodeficiency Syndrome
- Antigenic Variation
- Biological Evolution
- Cohort Studies
- Disease Progression
- HIV Envelope Protein gp120
- HIV Seropositivity
- HIV-1
- Homosexuality, Male
- Humans
- Immunocompetence
- Male
- Phenotype
- Phylogeny
- Prospective Studies
- Time Factors