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Article

Intrahost human immunodeficiency virus type 1 evolution is related to length of the immunocompetent period.

Journal of virology - 1 Nov 1995

Lukashov V V, Kuiken C L, Goudsmit J

Abstract excerpt

The antigenic diversity threshold theory predicts that antigenic sites of human immunodeficiency virus type 1, such as the V3 region of the external glycoprotein gp120, evolve more rapidly during the symptom-free period in individuals progressing to AIDS than in those who remain asymptomatic for a long time. To test this hypothesis, genomic RNA sequences were obtained from the sera of 44 individuals at...

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Identifiers

PMID: 7474108
DOI: 10.1128/JVI.69.11.6911-6916.1995
PMCID: PMC189608

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Source receipt: pubmed, retrieved 7 Sept 2026.

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