Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation of sweat chloride concentration with classes of the cystic fibrosis transmembrane conductance regulator gene mutations.

The Journal of pediatrics - 1 Nov 1995

Wilschanski M, Zielenski J, Markiewicz D, Tsui L C, Corey M, Levison H, Durie P R

Abstract excerpt

OBJECTIVE: To compare differences in epithelial chloride conductance according to class of mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. METHODS: We evaluated the relationship between the functional classes of CFTR mutations and chloride conductance using the first diagnostic sweat chloride concentration in a large cystic fibrosis (CF) population. RESULTS: There was no...

Topics

Child
Child, Preschool
Chlorides
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Genes, Regulator
Genotype
Heterozygote
Homozygote
Humans
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Retrospective Studies

Sweat

Source

Identifiers

PMID: 7472820
DOI: 10.1016/s0022-3476(95)70157-5

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7472820-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation of sweat chloride concentration with classes of the cystic fibrosis transmembrane conductance regulator gene mutations.PMID 7472820Read ↗

Correlating Cystic Fibrosis Transmembrane Conductance Regulator Function with Clinical Features to Inform Precision Treatment of Cystic FibrosisSemantic proximity Read ↗

Clinical phenotype and genotype of children with borderline sweat test and abnormal nasal epithelial chloride transport.Semantic proximity Read ↗

Genotype analysis and phenotypic manifestations of children with intermediate sweat chloride test results.Semantic proximity Read ↗

Phenotypic characterisation of patients with intermediate sweat chloride values: towards validation of the European diagnostic algorithm for cystic fibrosis.Semantic proximity Read ↗

Correlation of sweat chloride concentration with genotypes in cystic fibrosis patients in Saguenay Lac-Saint-Jean, Quebec, Canada.Semantic proximity Read ↗

Cystic fibrosis: genetics and intestinal secretion.Semantic proximity Read ↗

Variant cystic fibrosis phenotypes in the absence of CFTR mutations.Semantic proximity Read ↗

The relationship between sweat chloride levels and mortality in cystic fibrosis varies by individual genotype.Semantic proximity Read ↗

Association of sweat chloride concentration at time of diagnosis and CFTR genotype with mortality and cystic fibrosis phenotype.Semantic proximity Read ↗

How the sweat gland reveals levels of CFTR activity.Semantic proximity Read ↗

[From gene to disease; from defective chloride ion transport to cystic fibrosis].Semantic proximity Read ↗

Borderline sweat test: Utility and limits of genetic analysis for the diagnosis of cystic fibrosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.