Article
The relationship between sweat chloride levels and mortality in cystic fibrosis varies by individual genotype.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Jan 2018
Espel Julia C, Palac Hannah L, Bharat Ankit, Cullina Joanne, Prickett Michelle, Sala Marc, McColley Susanna A, Jain Manu
Abstract excerpt
RATIONALE: The association between CFTR genotype, sweat chloride and mortality has been inconsistent, but no previous analyses have examined the association stratified by individual genotypes. OBJECTIVES: To evaluate the genotype-specific association between sweat chloride and mortality. METHODS: The CFF Patient Registry was assessed and included all patients in the registry between 1996 and 2012 with at least...
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