Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlating Cystic Fibrosis Transmembrane Conductance Regulator Function with Clinical Features to Inform Precision Treatment of Cystic Fibrosis

19 Mar 2019

Abstract excerpt

Abstract Rationale The advent of precision treatment for cystic fibrosis using small-molecule therapeutics has created a need to estimate potential clinical improvements attributable to increases in cystic fibrosis transmembrane conductance regulator (CFTR) function. Objectives To derive CFTR function of a variety of CFTR genotypes and correlate with key clinical features (sweat chloride concentration, pancreatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cystic Fibrosis Research Advances
Share to Neonatal Respiratory Health Research
Share to Pharmaceutical studies and practices

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30888834
DOI: 10.1164/rccm.201901-0145oc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlating Cystic Fibrosis Transmembrane Conductance Regulator Function with Clinical Features to Inform Precision Treatment of Cystic FibrosisPMID 30888834Read ↗

Clinical and primary cell evidence reveals complex CFTR function–phenotype relationshipsSemantic proximity Read ↗

Advancing clinical development pathways for new CFTR modulators in cystic fibrosis.Semantic proximity Read ↗

Cystic Fibrosis: Modern Diagnostic and Therapeutic Advances from Molecular Pathogenesis to Multidisciplinary Management.Semantic proximity Read ↗

INTEGRATING GENOMIC AND FUNCTIONAL TESTING TO IMPROVE CFTR MODULATOR RESPONSE PREDICTION IN CHILDREN WITH CYSTIC FIBROSISSemantic proximity Read ↗

A new era in the treatment of cystic fibrosis: correction of the underlying CFTR defect.Semantic proximity Read ↗

A personalized medicine approach to optimize care for a pediatric cystic fibrosis patient with atypical clinical symptomsSemantic proximity Read ↗

Assessing accuracy of testing and diagnosis in cystic fibrosis.Semantic proximity Read ↗

ECFS standards of care on CFTR-related disorders: Diagnostic criteria of CFTR dysfunction.Semantic proximity Read ↗

Towards the pharmacogenomics of cystic fibrosis.Semantic proximity Read ↗

Association of sweat chloride concentration at time of diagnosis and CFTR genotype with mortality and cystic fibrosis phenotype.Semantic proximity Read ↗

Understanding CFTR Functionality: A Comprehensive Review of Tests and Modulator Therapy in Cystic Fibrosis.Semantic proximity Read ↗

Personalized medicine in cystic fibrosis: dawning of a new era.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.