Article
Correlation of sweat chloride concentration with genotypes in cystic fibrosis patients in Saguenay Lac-Saint-Jean, Quebec, Canada.
Clinical biochemistry - 1 Feb 1998
De Braekeleer M, Allard C, Leblanc J P, Aubin G, Simard F
Abstract excerpt
OBJECTIVES: Saguenay Lac-Saint-Jean, a geographically isolated region of northeastern Quebec has a high incidence of cystic fibrosis (CF) and three mutations only account for 94% of the CF chromosomes. The objective of the present study was to determine whether different mutations in the cystic f...
Topics
- Chlorides
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Genetic Testing
- Genotype
- Humans
- Incidence
- Point Mutation
- Quebec
- Sweat