Article
A successful program of immunizing Rh-negative male volunteers for anti-D production using frozen/thawed blood.
Transfusion - 1 Jan 2000
Urbaniak S J, Robertson A E
Abstract excerpt
Individually matched (rhesus-D) Rh-positive frozen/thawed red blood cells were used to immunize 28 Rh-negative male volunteers. The immunizing schedule consisted of a single unit (200 ml) of frozen/thawed red blood cells, followed by six monthly booster doses (0.5 to 1.0 ml) after a rest period of six months. A final response rate of 93 percent (26 of 28) was achieved. All responders had produced anti-D before...
Topics
- Antibody Formation
- Autoanalysis
- Erythrocyte Transfusion
- Freezing
- Genotype
- Humans
- Immunization
- Immunization, Secondary
- Male
- Rh-Hr Blood-Group System
- Time Factors