Article
Genetic and environmental influences on serum levels of human C4.
Annals of human biology - 1 Jan 2000
Averill B K, Bernal J E
Abstract excerpt
In a family study, levels of the C4 component of complement measured in 195 individuals show a continuous normal distribution. There is a slight but significant age effect, especially in females. Heritability is estimated at 62%. The effect of environment, however, remains substantial, and it is suggested that at some time during development the mechanism controlling the C4 levels establishes a general...
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