Article
Genetic and environmental factors influencing the human factor H plasma levels.
Immunogenetics - 1 May 2004
Esparza-Gordillo Jorge, Soria José Manuel, Buil Alfonso, Almasy Laura, Blangero John, Fontcuberta Jordi, Rodríguez de Córdoba Santiago
Abstract excerpt
Factor H is a plasma protein that plays a critical role in the regulation of complement activation in fluid phase and on cellular surfaces. Over the years numerous reports have illustrated the association of factor H deficiencies with chronic renal and infectious diseases. Plasma levels of factor H show a five-fold range of variation in humans (116-562 microg/ml), which may also be relevant to disease...
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