Article
Neurons induce contractions in myotubes containing only muscular dysgenic nuclei.
Muscle & nerve - 1 Jan 2000
Powell J A, Peterson A, Paul C V
Abstract excerpt
Muscular dysgenic (mdg/mdg) myotubes cultured alone do not contract. Glucosephosphate isomerase (GPI-1) isozymes were analyzed to determine the final genotype of cultured dysgenic (mdg/mdg, gpi-1a/a) myotubes to which normal embryonic spinal cord and limb cells (CBA/J +/+, gpi-1b/b) had been added. Although both myoblast and spinal cord cell additions caused induction of spontaneous contractions, only myoblasts...
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