Article
[Effect of the mutation muscular dysgenesis on the mitochondrial metabolism of fibroblasts in vitro].
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie - 1 Jan 1993
Aymard C, Malgat M, Mazat J P, Koenig J
Abstract excerpt
Muscular dysgenesis is a lethal mutation characterized by an absence of striated muscle contraction. This abnormality of function caused by a defect in excitation-contraction coupling is due to the lack of the alpha 1 subunit from the dihydropyridine receptor in the transverse tubule membrane. A...
Topics
- Electron Transport
- Fibroblasts
- In Vitro Techniques
- Mitochondria, Muscle
- Muscle Contraction
- Muscles
- Muscular Diseases
- Mutation
- Oxygen Consumption