Article
Sensitivity to the locomotor stimulant effects of ethanol and allopregnanolone is influenced by common genes.
Behavioral neuroscience - 1 Feb 2002
Palmer Abraham A, Miller Mark N, McKinnon Carrie S, Phillips Tamara J
Abstract excerpt
Allopregnanolone is a neuroactive steroid that, like ethanol (EtOH), has stimulant, anxiolytic, ataxic, and depressant effects. Two experiments tested the hypothesis that sensitivity to the locomotor stimulant effects of these drugs is influenced by a common set of genes. Sensitivity to the locomotor stimulant effects of allopregnanolone was determined in 24 BXD recombinant inbred (RI) strains. Strain means were...
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