Article
Alcohol acceptance, preference, and sensitivity in mice. I. Quantitative genetic analysis using BXD recombinant inbred strains.
Alcoholism, clinical and experimental research - 1 Dec 1994
Rodriguez L A, Plomin R, Blizard D A, Jones B C, McClearn G E
Abstract excerpt
Although the recombinant inbred strain method was designed for molecular genetic analysis of linkage, it also provides powerful quantitative genetic analyses of heritability and genetic correlations. Measures of alcohol acceptance, alcohol preference, and hypnotic dose sensitivity (HDS) were assessed in 21 strains of mice from the BXD RI series. Sex differences were found to be significant at a phenotypic level....
Topics
- Alcohol Drinking
- Alcoholism
- Animals
- Choice Behavior
- Female
- Genetic Linkage
- Male
- Mice
- Mice, Inbred Strains
- Motivation
- Phenotype