Article
Mutagenicity examination of several non-steroidal anti-inflammatory drugs in bacterial systems.
Mutation research - 1 Jan 2000
Kadotani S, Arisawa M, Maruyama H B
Abstract excerpt
The mutagenicity of 6 marketed non-steroidal anti-inflammatory drugs (aspirin, flufenamic acid, diclofenac sodium, indomethacin, naproxen and chloroquine) as well as 2 new anti-inflammatory drugs (tenoxicam and carprofen) was examined by using in vitro bacterial systems (repair test and reversion test). None of them was mutagenic on Ames' reversion test. However, they differed in their responses to repair tests....
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