Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Antimutagenic and anti-oxidant activities of the non-steroidal anti-inflammatory drug celecoxib.

Clinical and experimental pharmacology & physiology - 1 Oct 2005

Ajith Ta, Subin J P, Jacob J, Sanjay P S, Babitha N V

Abstract excerpt

1. Tumors arise and progress through the accumulation of serial genetic changes, including successive mutations, which involve activation of proto-oncogenes and inactivation of tumour suppressor genes, leading to the uncontrolled proliferation of progeny cells. The human body is continuously and unavoidably exposed to structurally diverse chemicals with established carcinogenic activity in animal models and/or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 2-Acetylaminofluorene
Share to 9,10-Dimethyl-1,2-benzanthracene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antimutagenic Agents

Share to Free Radical Scavengers

Share to Methylnitronitrosoguanidine

Share to Phenylenediamines

Share to Sodium Azide

Share to Superoxides

Source

Identifiers

PMID: 16173952
DOI: 10.1111/j.1440-1681.2010.04280.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Antimutagenic and anti-oxidant activities of the non-steroidal anti-inflammatory drug celecoxib.PMID 16173952Read ↗

The genetic toxicology of paracetamol and aspirin: a review.Semantic proximity Read ↗

Cytotoxic effects of dimethyl-celecoxib (DMC) on bone tumor cell line MG63 and cell line HEK293Semantic proximity Read ↗

Genotoxicity and carcinogenicity studies of analgesics, anti-inflammatory drugs and antipyretics.Semantic proximity Read ↗

A comparative study on the antimutagenicity of atorvastatin and lovastatin against directly acting mutagens.Semantic proximity Read ↗

Two novel aspirin analogues show selective cytotoxicity in primary chronic lymphocytic leukaemia cells that is associated with dual inhibition of Rel A and COX-2Semantic proximity Read ↗

Growth inhibitory effect of celecoxib and rofecoxib on human colorectal carcinoma cell lines.Semantic proximity Read ↗

In vitro and in vivo molecular analysis of cyclooxygenase-2 (COX-2)-dependent and COX-2 independent cytoprotective pathways in the vascular endotheliumSemantic proximity Read ↗

Mutagenicity examination of several non-steroidal anti-inflammatory drugs in bacterial systems.Semantic proximity Read ↗

Evaluation of the in vitro antimutagenic effect of Doash tea aqueous extracts.Semantic proximity Read ↗

Inhibition of COX-2 and induction of apoptosis: two determinants of nonsteroidal anti-inflammatory drugs' chemopreventive efficacies in mouse lung tumorigenesis.Semantic proximity Read ↗

Biodistribution of, antimutagenic efficacies in Salmonella typhimurium of, and inhibition of P450 activities by ellagic acid and one analogue.Semantic proximity Read ↗

Isolation and structural identification of a direct-acting mutagen derived from N-nitroso-N-methylpentylamine and Fenton's reagent with copper ion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.