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Article

Protective effect of R-factor plasmid pKM101 on lethal damage by UV and chemical mutagens in E. coli strains with different DNA-repairing capacities.

Mutation research - 1 Jan 2000

Nunoshiba T, Nishioka H

Abstract excerpt

The sensitivities of 8 R-factor plasmid pKM101-mediated E. coli strains with different DNA-repairing capacities to UV, AF-2 and MMS were investigated. The clear protective effect of pKM101 to lethal damage induced by these agents was only seen in the recA+ lexA+ and the uvr- lex- strains. The results support the hypothesis that the protective effect of pKM101 depends on the recA+ genotype. It is also possible to...

Topics

DNA Repair
Dose-Response Relationship, Radiation
Escherichia coli
Furylfuramide
Genes, Bacterial
Genes, Lethal
Methyl Methanesulfonate
Mutagens
Mutation
Nitrofurans
R Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Species Specificity

Ultraviolet Rays

Source

Identifiers

PMID: 6392877
DOI: 10.1016/0165-7992(84)90085-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-6392877-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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