The ultraviolet-sensitizing function of plasmid R391 interferes with a late step of postreplication repair in Escherichia coli.

doi:10.1016/0921-8777(95)00044-5

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Article

The ultraviolet-sensitizing function of plasmid R391 interferes with a late step of postreplication repair in Escherichia coli.

Mutation research - 2 Apr 1996

Wang T C, de Saint Phalle B, Millman K L, Fowler R G

Abstract excerpt

The conjugative plasmid R391 increases the UV radiation sensitivity of wild-type, uvrA, and lexA cells of Escherichia coli, but not recA strains. To investigate the UV-sensitizing function of R391, we examined the effect of R391 on the repair of DNA daughter-strand gaps and on the UV radiation sensitivities of various repair and/or recombination-deficient mutants. The presence of R391 did not significantly...

Topics

Conjugation, Genetic
DNA Repair
DNA Replication
Dose-Response Relationship, Radiation
Escherichia coli
Genotype
R Factors
Recombination, Genetic
Ultraviolet Rays

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Identifiers

PMID: 8637500
DOI: 10.1016/0921-8777(95)00044-5

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