Article
Complementation of a pKM101 derivative that decreases resistance to UV killing but increases susceptibility to mutagenesis.
Mutation research - 1 Jan 2000
Langer P J, Perry K L, Walker G C
Abstract excerpt
The drug resistance plasmid pKM101 makes Escherichia coli resistant to the lethal effects of ultraviolet (UV) irradiation and more susceptible to mutagenesis by a variety of agents. The plasmid operon responsible for increasing mutagenesis has been termed mucAB (Mutagenesis, UV and chemical). We...
Topics
- Bacterial Proteins
- Chromosome Mapping
- DNA Repair
- DNA Restriction Enzymes
- DNA, Bacterial
- Escherichia coli
- Genetic Complementation Test
- Methyl Methanesulfonate
- Mutation
- Operon
- R Factors
- Rec A Recombinases
- Serine Endopeptidases
- Ultraviolet Rays