Article
The relationship between ethanol-induced locomotor activation and narcosis in long-sleep and short-sleep mice.
Alcoholism, clinical and experimental research - 1 Jan 2000
Dudek B C, Abbott M E
Abstract excerpt
Mice selectively bred for marked response to hypnotic doses of ethanol (long-sleep, LS) respond to subhypnotic doses of ethanol (ETOH) with less stimulation of locomotor activity than their short-sleep (SS) counterparts. This assessment was made by comparing ETOH-induced alterations in locomotor activity to an untreated baseline within individual subjects, and to a saline-treated control group. A correlational...
Topics
- Animals
- Ethanol
- Hybridization, Genetic
- Mice
- Mice, Inbred Strains
- Motor Activity
- Phenotype
- Reflex
- Selection, Genetic
- Sleep Stages