Article
Fetal alcohol effects in long- and short-sleep mice: activity, passive avoidance, and in utero ethanol levels.
Neurotoxicology and teratology - 1 Jan 2000
Gilliam D M, Stilman A, Dudek B C, Riley E P
Abstract excerpt
Genetic differences in susceptibility to fetal alcohol effects (FAE) have been suggested by both human and animal studies. The Long-Sleep (LS) and Short-Sleep (SS) mouse lines, selectively bred for differences in ethanol-induced narcosis, provide a model for studying differential alcohol sensitivity in the etiology of FAE. LS and SS mice were intubated with either 2.9 g/kg (20% w/v) ethanol (E) or an isocaloric...
Topics
- Animals
- Avoidance Learning
- Drug Resistance
- Ethanol
- Female
- Fetal Alcohol Spectrum Disorders
- Genotype
- Mice
- Motor Activity
- Pregnancy
- Sleep
