Article
Distribution of HLA-B*27 subtypes in Tunisians and their association with ankylosing spondylitis.
Joint bone spine - 1 Mar 2008
Ben Radhia Karima, Ayed-Jendoubi Saloua, Sfar Imene, Ben Romdhane Thouraya, Makhlouf Mouna, Gorgi Yousr, Ayed Khaled
Abstract excerpt
OBJECTIVE: The human leukocyte antigen HLA-B27 is a class I antigen of the major histocompatibility complex strongly associated with ankylosing spondylitis (AS) and other related spondyloarthropathies (SpAs). The mechanism of this association remains unknown. HLA-B27 is a serologic specificity that represents a family of at least 25 different HLA-B27 alleles (2701-2725). These alleles are closely related by...
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