HLA-B27-derived peptides as autoantigens for T lymphocytes in ankylosing spondylitis.

doi:10.1002/art.1780401118

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Article

HLA-B27-derived peptides as autoantigens for T lymphocytes in ankylosing spondylitis.

Arthritis and rheumatism - 1 Nov 1997

Märker-Hermann E, Meyer zum Büschenfelde K H, Wildner G

Abstract excerpt

OBJECTIVE: To study whether peptides derived from the HLA-B27 molecule sequence can stimulate peripheral blood T lymphocytes (PBL) from patients with HLA-B27-associated spondylarthropathies. METHODS: PBL from 55 HLA-B27+ patients with ankylosing spondylitis (AS), 28 HLA-B27+ patients with other s...

Topics

Adolescent
Adult
Aged
Autoantigens
Cell Line
Enzyme-Linked Immunosorbent Assay
Female
Flow Cytometry
HLA-B27 Antigen
Humans
Interferon-gamma
Lymphocyte Activation
Male
Middle Aged
Peptides
Phenotype
Receptors, Antigen, T-Cell, gamma-delta
Spondylitis, Ankylosing

Source

Open in PubMed

Identifiers

PMID: 9365095
DOI: 10.1002/art.1780401118

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9365095-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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