Article
HLA-B27-derived peptides as autoantigens for T lymphocytes in ankylosing spondylitis.
Arthritis and rheumatism - 1 Nov 1997
Märker-Hermann E, Meyer zum Büschenfelde K H, Wildner G
Abstract excerpt
OBJECTIVE: To study whether peptides derived from the HLA-B27 molecule sequence can stimulate peripheral blood T lymphocytes (PBL) from patients with HLA-B27-associated spondylarthropathies. METHODS: PBL from 55 HLA-B27+ patients with ankylosing spondylitis (AS), 28 HLA-B27+ patients with other spondylarthropathies, 7 rheumatoid arthritis patients, and 30 HLA-B27+ and 22 HLA-B27- healthy controls were tested in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
