Article
Risk of haematological malignancies in HLA-B27 carriers.
British journal of haematology - 1 Nov 2001
Au W Y, Hawkins B R, Cheng N, Lie A K, Liang R, Kwong Y L
Abstract excerpt
Human leucocyte antigen (HLA)-B27 carriers are predisposed to inflammatory and autoimmune diseases. Among 1137 patients with haematological diseases, 59 HLA-B27 carriers were identified. Compared with 18 774 volunteers, the incidence of HLA-B27 was increased in patients with acute leukaemia (relative risk RR = 1.67, P = 0.002), for both acute myeloid leukaemia (AML) (RR) = 1.67, P = 0.007) and acute lymphoblastic...
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