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Article

The c-Ha-ras1, insulin and beta-globin loci map outside the deletion associated with aniridia-Wilms' tumour.

Nature - 1 Jan 2000

de Martinville B, Francke U

Abstract excerpt

The localization of protooncogenes on human chromosomes may coincide with chromosome breakpoints of consistent translocations in leukaemias or lymphomas, suggesting a direct involvement of oncogenes in carcinogenesis. For example, in Burkitt's lymphoma consistent translocations may be associated with rearrangements of c-myc. Our assignment of the c-Harvey-ras1 oncogene to chromosome 11, precisely to region 11p11...

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Identifiers

PMID: 6312329
DOI: 10.1038/305641a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 9 closest

The c-Ha-ras1, insulin and beta-globin loci map outside the deletion associated with aniridia-Wilms' tumour.PMID 6312329Read ↗

The beta-subunit of follicle-stimulating hormone is deleted in patients with aniridia and Wilms' tumour, allowing a further definition of the WAGR locus.Semantic proximity Read ↗

The distal region of 11p13 and associated genetic diseases.Semantic proximity Read ↗

Evaluation of chromosome 11p imbalances in aniridia and Wilms tumor patients.Semantic proximity Read ↗

Pericentric intrachromosomal insertion responsible for recurrence of del(11)(p13p14) in a family.Semantic proximity Read ↗

Loss of a Harvey ras allele in sporadic Wilms' tumour.Semantic proximity Read ↗

Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours.Semantic proximity Read ↗

A panel of restriction fragment length polymorphisms for chromosomal band 11p13.Semantic proximity Read ↗

A FISH approach to defining the extent and possible clinical significance of deletions at the WAGR locus.Semantic proximity Read ↗

A nude mouse Wilms' tumor line (KCMC-WT-1) derived from an aniridia patient with monoalleleic partial deletion of chromosome 11p.Semantic proximity Read ↗

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