The c-Ha-ras1, insulin and beta-globin loci map outside the deletion associated with aniridia-Wilms' tumour.

doi:10.1038/305641a0

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Article

The c-Ha-ras1, insulin and beta-globin loci map outside the deletion associated with aniridia-Wilms' tumour.

Nature - 1 Jan 2000

de Martinville B, Francke U

Abstract excerpt

The localization of protooncogenes on human chromosomes may coincide with chromosome breakpoints of consistent translocations in leukaemias or lymphomas, suggesting a direct involvement of oncogenes in carcinogenesis. For example, in Burkitt's lymphoma consistent translocations may be associated...

Topics

Alleles
Child, Preschool
Chromosome Banding
Chromosome Deletion
Chromosomes, Human, 6-12 and X
Crossing Over, Genetic
DNA Restriction Enzymes
Female
Genes
Globins
Humans
Infant
Infant, Newborn
Insulin
Iris
Karyotyping
Kidney Neoplasms
Male

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