Article
Pericentric intrachromosomal insertion responsible for recurrence of del(11)(p13p14) in a family.
Genes, chromosomes & cancer - 1 May 1993
Henry I, Hoovers J, Barichard F, Berthéas M F, Puech A, Prieur F, Gessler M, Bruns G, Mannens M, Junien C
Abstract excerpt
The combined use of qualitative and quantitative analysis of 11p13 polymorphic markers together with chromosomal in situ suppression hybridization (CISS) with biotin labeled probes mapping to 11p allowed us to characterize a complex rearrangement segregating in a family. We detected a pericentric...
Topics
- Child
- Chromosome Banding
- Chromosome Deletion
- Chromosomes, Human, Pair 11
- Cosmids
- DNA Transposable Elements
- Family
- Female
- Genetic Markers
- Genotype
- Humans
- Kidney Neoplasms
- Male
- Pedigree
- Restriction Mapping
- Wilms Tumor