Article
Digital image analysis of chromatin fibre phenotype after "in situ' digestion with restriction endonucleases.
Cell biology international - 1 Mar 1996
Gosálvez J, López-Fernández C, Fernández J L, Goyanes V J, Buño I
Abstract excerpt
Restriction Endonucleases (REs) may recognize, cleave and remove DNA from fixed chromatin producing specific chromosome banding patterns. However, the modifications produced in the chromatin fibre are not easy to evaluate and compare. The aim of the present investigation was to visualize differen...
Topics
- Animals
- Cell Line
- Chromatin
- Chromosomes
- Color
- DNA Restriction Enzymes
- Deoxyribonuclease HpaII
- Deoxyribonucleases, Type II Site-Specific
- Image Processing, Computer-Assisted
- Mice
- Microscopy, Electron
- Phenotype