Article
[Molecular mechanisms of 2-aminopurine and 2,6-diaminopurine induced mutations].
Molekuliarnaia biologiia - 1 Jan 2000
Poltev V I, Shuliupina N V, Bruskov V I
Abstract excerpt
Molecular mechanisms of base pair substitutions induced by 2-aminopurine and 2,6-diaminopurine have been proposed by calculations of nonbonded interaction energy of this substances with nucleic acid bases. The calculation results suppose that the main pathways of the transitions are wobble pair formations of these analogues with cytosine. The possibility of the transversions as a result of incorporation of...
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