[Molecular mechanisms of 2-aminopurine and 2,6-diaminopurine induced mutations].

Article

[Molecular mechanisms of 2-aminopurine and 2,6-diaminopurine induced mutations].

Molekuliarnaia biologiia - 1 Jan 2000

Poltev V I, Shuliupina N V, Bruskov V I

Abstract excerpt

Molecular mechanisms of base pair substitutions induced by 2-aminopurine and 2,6-diaminopurine have been proposed by calculations of nonbonded interaction energy of this substances with nucleic acid bases. The calculation results suppose that the main pathways of the transitions are wobble pair f...

Topics

2-Aminopurine
Adenine
Base Sequence
DNA
Molecular Conformation
Mutation
Structure-Activity Relationship

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