Mass Spectrometry-Based Profiling of Personalized Immunopeptidomes in Thai Renal Cell Carcinoma.

doi:10.1021/acs.jproteome.6c00141

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Article

Mass Spectrometry-Based Profiling of Personalized Immunopeptidomes in Thai Renal Cell Carcinoma.

Journal of proteome research - 4 Sept 2026

Somparn Poorichaya, Sriswasdi Sira, Wongkongkathep Piriya, Techachakrit Jirapat, Muanwien Phijitra, Nanthawong Saharat, Apinan Tatchapon, Opanuraks Julin, Shuangshoti Shanop, Hirankarn Nattiya, Moonmuang Sutpirat, Kampoun Tanyaluck, Chaiyawat Parunya, Pisitkun Trairak

Abstract excerpt

This study profiles the personalized immunopeptidomes of 13 Thai patients with renal cell carcinoma (RCC), addressing a critical knowledge gap in Southeast Asian populations characterized by distinct HLA allele distributions. We combined whole-exome sequencing (WES)-based personalized proteome construction with liquid chromatography-tandem mass spectrometry (LC-MS/MS), using both database-driven searches and de...

Read the complete abstract on PubMed

Topics

Humans
Carcinoma, Renal Cell
Kidney Neoplasms
Tandem Mass Spectrometry
Antigens, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Thailand

Exome Sequencing

Proteome

Peptides

Male

Female

Alleles

Liquid Chromatography-Mass Spectrometry

Middle Aged

Proteomics

Source

Open in PubMed

Identifiers

PMID: 42695889
DOI: 10.1021/acs.jproteome.6c00141

Genes

JADE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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