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Article

Disentangling the association between chronic pain and sarcopenia-related traits: A bidirectional Mendelian randomization study.

The Journal of international medical research - 1 Sept 2026

Wang Weijie, Zhang Qiankun, Wu Zhenhua

Abstract excerpt

ObjectiveThis study aimed to investigate the potential causal relationships between chronic pain and three key sarcopenia-related quantitative traits: (a) hand grip strength; (b) usual walking pace; and (c) appendicular lean mass, using bidirectional two-sample Mendelian randomization.MethodsWe conducted bidirectional two-sample Mendelian randomization using summary-level data from large-scale genome-wide...

Read the complete abstract on PubMed

Topics

Humans
Sarcopenia
Hand Strength
Mendelian Randomization Analysis
Chronic Pain
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Musculoskeletal Pain

Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 42684940
DOI: 10.1177/03000605261478538
PMCID: PMC13539023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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