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Article

Causal Links Between Sleep Duration and Sarcopenia-Related Phenotypes: A Mendelian Randomization and Shared Genetic Mechanism Study.

American journal of physical medicine & rehabilitation - 1 Jun 2026

Shang Haibin, Deng Zhen, Lian Youzhi, Ai Youli, Zhang Jie, Li Guozhong

Abstract excerpt

BACKGROUND: Emerging observational research reported that sleep duration was linked to sarcopenia, yet these associations have not been ascertained causally. METHOD: This study included data from the 2015-2018 National Health and Nutrition Examination Survey and applied multivariable logistic regression to evaluate the relationship between sleep duration and sarcopenia. A two-sample Mendelian randomization study...

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Identifiers

PMID: 42192271
DOI: 10.1097/PHM.0000000000002921
PMCID: PMC13196859

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