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Article

Recurrent parasitemias with artemisinin partial resistance mutations during the 2024 Ethiopia malaria resurgence: a case series.

Malaria journal - 31 Jul 2026

Geleta Dessalegn, Brhane Bokretsion G, Abera Adugna, Belachew Mahlet, Sime Heven, Gebreegziaxher Atsbeha, Getu Melak, Ali Abraham, Tesfay Neamin, Habtetsion Medhanye, Kokobe Belayneh, Kebede Mandefro, Worku Zemene, Tasew Geremew, Tadesse Gemechu, Tollera Getachew, Fola Abebe A, Bailey Jeffrey A, Juliano Jonathan J, Parr Jonathan B, Abte Melkamu, Assefa Ashenafi

Abstract excerpt

BACKGROUND: Ethiopia experienced a marked resurgence of malaria in 2024. Artemisinin-based combination therapies (ACTs) are first-line treatment for uncomplicated Plasmodium falciparum malaria and are threatened by the emergence of artemisinin partial resistance (ART-R), which is associated with mutations in the P. falciparum kelch13 (k13) gene, that could undermine treatment efficacy and accelerate transmission....

Read the complete abstract on PubMed

Topics

Ethiopia
Artemisinins
Drug Resistance
Plasmodium falciparum

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Humans

Antimalarials

Malaria, Falciparum

Mutation

Parasitemia

Female

Male

Recurrence

Child

Adult

Adolescent

Child, Preschool

Protozoan Proteins

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 42681629
DOI: 10.1186/s12936-026-06078-6
PMCID: PMC13536858

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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