Dietary-Derived Corchorus olitorius L. Extract Suppresses KRAS-Mutant Pancreatic Cancer by Activating Ferritinophagy-Dependent Ferroptosis.

doi:10.1111/1750-3841.71410

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Article

Dietary-Derived Corchorus olitorius L. Extract Suppresses KRAS-Mutant Pancreatic Cancer by Activating Ferritinophagy-Dependent Ferroptosis.

Journal of food science - 1 Sept 2026

Tseng Chiao-Yun, Lin Hui-Hsuan, Chyau Charng-Cherng, Yu Pei-Rong, Liang Yu-Hsuan, Wong Yueching, Chen Jing-Hsien

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterized by frequent activating mutations in the Kirsten rat sarcoma viral oncogene homologue (KRAS) and limited therapeutic options. Corchorus olitorius L., a traditional edible plant widely consumed in Asia, possesses documented anti-inflammatory properties; however, its anticancer potential remains unclear. This study investigated...

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PMID: 42667123
DOI: 10.1111/1750-3841.71410
PMCID: PMC13525489

Genes

KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.