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Article

XRCC1, but not APE1 and hOGG1 gene polymorphisms is a risk factor for pterygium.

Molecular vision - 4 Jun 2010

Chen Pei-Liang, Yeh Kun-Tu, Tsai Yi-Yu, Koeh Hank, Liu Yu-Ling, Lee Huei, Cheng Ya-Wen

Abstract excerpt

PURPOSE: Epidemiological evidence suggests that UV irradiation plays an important role in pterygium pathogenesis. UV irradiation can produce a wide range of DNA damage. The base excision repair (BER) pathway is considered the most important pathway involved in the repair of radiation-induced DNA...

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Source

Open in PubMed Open full text

Identifiers

PMID: 20577654
PMCID: PMC2890553

Genes

XRCC1
OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20577654-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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XRCC1, but not APE1 and hOGG1 gene polymorphisms is a risk factor for pterygium.PMID 20577654Read ↗

Pterygium and genetic polymorphisms of the DNA repair enzymes XRCC1, XPA, and XPD.Semantic proximity Read ↗

Pterygium and genetic polymorphism of DNA double strand break repair gene Ku70.Semantic proximity Read ↗

Genetic polymorphism of hOGG1 and risk of pterygium in Chinese.Semantic proximity Read ↗

CYP1A1 gene polymorphisms as a risk factor for pterygium.Semantic proximity Read ↗

Common polymorphisms of the hOGG1, APE1 and XRCC1 genes correlate with the susceptibility and clinicopathological features of primary angle-closure glaucoma.Semantic proximity Read ↗

Contribution of Radiation Sensitive Protein 51 Genotypes to Pterygium Risk in a Taiwanese Population.Semantic proximity Read ↗

Genetic polymorphisms in XRCC1, OGG1, and XRCC3 DNA repair genes and DNA damage in radiotherapy workers.Semantic proximity Read ↗

Xeroderma Pigmentosum C (XPC) Mutations in Primary Fibroblasts Impair Base Excision Repair Pathway and Increase Oxidative DNA DamageSemantic proximity Read ↗

Senile cataract and genetic polymorphisms of APE1, XRCC1 and OGG1.Semantic proximity Read ↗

Null type of glutathione S-transferase M1 polymorphism is associated with early onset pterygium.Semantic proximity Read ↗

Genetic variants of the APE1 gene and the risk of vitiligo in a Chinese population: a genotype-phenotype correlation study.Semantic proximity Read ↗

Mechanisms and biomarker candidates in pterygium developmentSemantic proximity Read ↗

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