Dysregulation of circ-SMARCA5, circ-RHOT1, and HNF1A and the association of HNF1A polymorphisms with hepatocellular carcinoma.

Abstract excerpt

INTRODUCTION: Hepatocellular carcinoma (HCC) accounts for many cancer-related morbidity and mortality cases. This study aimed to assess the expression of circ-SMARCA5, circ-RHOT1, and hepatocyte nuclear factor 1 homeobox A (HNF1A). Analyze the protein expression of HNF1A, and identify HNF1A polymorphism and its correlation with HCC incidence and staging. METHODS: In this study, 48 HCC patients and 48 age-matched...

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