Association of Interleukin 1 Receptor Antagonist (IL1RN) rs4251961 with Periodontitis Risk in Portuguese Postpartum Women: A Pilot Study.

doi:10.3390/ijms27167310

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Article

Association of Interleukin 1 Receptor Antagonist (IL1RN) rs4251961 with Periodontitis Risk in Portuguese Postpartum Women: A Pilot Study.

International journal of molecular sciences - 16 Aug 2026

Couceiro Joana, Família Carlos, Brito José, Mendes José João, Baptista Pedro V, Fernandes Alexandra R, Quintas Alexandre

Abstract excerpt

Periodontitis (PD), the second most prevalent oral disease, contributes to systemic health issues and results from a complex interaction between microbial dysbiosis and host immune responses, strongly shaped by genetic background. This pilot case-control study evaluated associations between five inflammation-related variants (IL1A rs1800587, IL1B rs1143634, IL1B rs16944, IL1RN rs4251961, TNFA rs1800629) and PD...

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Share to Polymorphism, Single Nucleotide
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Identifiers

PMID: 42653313
DOI: 10.3390/ijms27167310
PMCID: PMC13513210

Genes

IL1RN
IL1B
IL1A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.