Article
Association of OPG, TNF-α, and IL-1B Gene Variants With Periodontitis in a South African Population.
International dental journal - 1 Aug 2026
Kabbashi Salma, Ngwa Ndonwi Elvis, Holmes Haly, Prince Yvonne, Chetty Manogari
Abstract excerpt
AIM: This study aimed to investigate candidate single-nucleotide polymorphisms linked to periodontitis susceptibility in a Western Cape cohort, providing insights into population-specific host genetic factors. MATERIALS AND METHODS: This observational case-control study recruited a total of 150 S...
Topics
- Humans
- Female
- Osteoprotegerin
- South Africa
- Case-Control Studies
- Male
- Polymorphism, Single Nucleotide
- Tumor Necrosis Factor-alpha
- Periodontitis
- Interleukin-1beta
- Genetic Predisposition to Disease
- Adult
- Middle Aged
- Genotype
- Gene Frequency