Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of OPG, TNF-α, and IL-1B Gene Variants With Periodontitis in a South African Population.

International dental journal - 1 Aug 2026

Kabbashi Salma, Ngwa Ndonwi Elvis, Holmes Haly, Prince Yvonne, Chetty Manogari

Abstract excerpt

AIM: This study aimed to investigate candidate single-nucleotide polymorphisms linked to periodontitis susceptibility in a Western Cape cohort, providing insights into population-specific host genetic factors. MATERIALS AND METHODS: This observational case-control study recruited a total of 150 South African participants. Saliva samples were genotyped using the OpenArray QuantStudio 12K Flex qPCR System. Genotype...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to TNF gene

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to South Africa

Share to Tumor Necrosis Factor-alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 42086006
DOI: 10.1016/j.identj.2026.109606
PMCID: PMC13158762

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of OPG, TNF-α, and IL-1B Gene Variants With Periodontitis in a South African Population.PMID 42086006Read ↗

INTERLEUKIN-1 GENE POLYMORPHISMS AND SUSCEPTIBILITY TO PERIODONTITIS ACROSS ETHNICITIES AND POPULATIONS: A LITERATURE REVIEW.Semantic proximity Read ↗

Association between Interleukin-1β Gene -511C>T/+3954C>T Polymorphisms and Aggressive Periodontitis Susceptibility: Evidence from a Meta-Analysis.Semantic proximity Read ↗

Polymorphic Regions in Fc Gamma Receptor and Tumor Necrosis Factor-α Genes and Susceptibility to Chronic Periodontitis in a Cohort From South India.Semantic proximity Read ↗

Impact of IL-17A rs2275913 allelic variation on periodontitis susceptibility: evidence from a meta-analysis.Semantic proximity Read ↗

Interleukin-6-174G/C Polymorphism Contributes to Periodontitis Susceptibility: An Updated Meta-Analysis of 21 Case-Control Studies.Semantic proximity Read ↗

Association of IL-10 -1082A>G, -819C>T, and -592C>A polymorphisms with susceptibility to chronic and aggressive periodontitis: a systematic review and meta-analysis.Semantic proximity Read ↗

Single nucleotide polymorphisms as a predisposing factor for the development of apical periodontitis-An umbrella review.Semantic proximity Read ↗

Genetic polymorphisms and periodontal disease in populations of African descent: A review.Semantic proximity Read ↗

Detection of risk SNPs and periopathogenic bacteria in periodontitis patients and healthy individuals in Slovak populationSemantic proximity Read ↗

Genetic Susceptibility to PeriodontitisSemantic proximity Read ↗

Chronic Periodontitis and Immunity, Towards the Implementation of a Personalized Medicine: A Translational Research on Gene Single Nucleotide Polymorphisms (SNPs) Linked to Chronic Oral Dysbiosis in 96 Caucasian PatientsSemantic proximity Read ↗

Immunomodulatory factors gene polymorphisms in chronic periodontitis: an overviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.