Article
Influence of inflammasome NLRP3, and IL1B and IL2 gene polymorphisms in periodontitis susceptibility.
PloS one - 1 Jan 2020
de Alencar Josiane Bazzo, Zacarias Joana Maira Valentini, Tsuneto Patrícia Yumeko, Souza Victor Hugo de, Silva Cléverson de Oliveira E, Visentainer Jeane Eliete Laguila, Sell Ana Maria
Abstract excerpt
The pathogenesis of periodontitis (PD) involves several molecules of the immune system that interact in a network to eliminate the periodontopathogens, yet, they contribute to periodontal tissue destruction. The different mechanisms that lead to periodontal tissue damage are not clear. Despite this, immune response genes have been related to the development of PD previously, such as those involved in...
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