Article
Association of interleukin-1 gene polymorphisms with early-onset periodontitis.
Journal of clinical periodontology - 1 Sept 2000
Parkhill J M, Hennig B J, Chapple I L, Heasman P A, Taylor J J
Abstract excerpt
BACKGROUND, AIMS: Early-onset periodontal diseases (EOP) are a group of inflammatory disorders characterised by a rapid rate of periodontal tissue destruction, in young individuals who are otherwise healthy. There is now substantial evidence to suggest that genetic factors play a rôle in the pathogenesis of EOP but the precise nature of these factors remains unclear. Polymorphisms in cytokine genes which may...
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