Role of Mechanotransduction in Cancer: A Complex Problem Involving Gene Mutations and Altered Levels of Connection Components.

doi:10.3390/biom16081147

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Article

Role of Mechanotransduction in Cancer: A Complex Problem Involving Gene Mutations and Altered Levels of Connection Components.

Biomolecules - 7 Aug 2026

Silver Frederick H

Abstract excerpt

BACKGROUND: External and internal forces and tissue energy influence the structure and function of mammalian tissues during life in a gravitational field. Changing force (stress) and energy equilibria provide a dynamic means to regulate cell and tissue growth during development and maturation. However, genetic mutations and changes in expression of macromolecules involved in cell and extracellular matrix (ECM)...

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PMID: 42650813
DOI: 10.3390/biom16081147
PMCID: PMC13510967

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