Article
Mechanotransduction gone awry.
Nature reviews. Molecular cell biology - 1 Jan 2009
Jaalouk Diana E, Lammerding Jan
Abstract excerpt
Cells sense their physical surroundings through mechanotransduction - that is, by translating mechanical forces and deformations into biochemical signals such as changes in intracellular calcium concentration or by activating diverse signalling pathways. In turn, these signals can adjust cellular and extracellular structure. This mechanosensitive feedback modulates cellular functions as diverse as migration,...
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