Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanotransduction in tumor progression: The dark side of the force

21 Feb 2018

Abstract excerpt

Cancer has been characterized as a genetic disease, associated with mutations that cause pathological alterations of the cell cycle, adhesion, or invasive motility. Recently, the importance of the anomalous mechanical properties of tumor tissues, which activate tumorigenic biochemical pathways, has become apparent. This mechanical induction in tumors appears to consist of the destabilization of adult tissue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Mechanics and Interactions
Share to Erythrocyte Function and Pathophysiology
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29467174
DOI: 10.1083/jcb.201701039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanotransduction in tumor progression: The dark side of the forcePMID 29467174Read ↗

Cancer cell mechanobiology: a new frontier for cancer researchSemantic proximity Read ↗

Cellular mechanobiology and cancer metastasisSemantic proximity Read ↗

Deleterious Mechanical Deformation Selects Mechanoresilient Cancer Cells with Enhanced Proliferation and Chemoresistance.Semantic proximity Read ↗

Mechanisms and impact of altered tumour mechanics.Semantic proximity Read ↗

The matrix environmental and cell mechanical properties regulate cell migration and contribute to the invasive phenotype of cancer cellsSemantic proximity Read ↗

Alterations of Cytoskeleton Networks in Cell Fate Determination and Cancer DevelopmentSemantic proximity Read ↗

Biophysical perspectives to understanding cancer-associated fibroblastsSemantic proximity Read ↗

Dynamic links between mechanical forces and metabolism shape the tumor milieu.Semantic proximity Read ↗

Biophysics of Tumor Microenvironment and Cancer Metastasis - A Mini ReviewSemantic proximity Read ↗

Mechanosensitive Ion Channel PIEZO1 Signaling in the Hall-Marks of Cancer: Structure and FunctionsSemantic proximity Read ↗

Mechano-signaling of prostate tumor initiating cells facilitates their tropism to stiff metastatic nicheSemantic proximity Read ↗

Tumor-induced solid stress activates β-catenin signaling to drive malignant behavior in normal, tumor-adjacent cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.