Article
Genetics of breast cancer: management strategies and risk-reducing surgery.
British journal of hospital medicine (London, England : 2005) - 2 Dec 2019
Balasubramanian Rajesh, Rolph Rachel, Morgan Catrin, Hamed Hisham
Abstract excerpt
The last two decades have witnessed major advances in genetic sequencing which have led to more accurate identification of women at risk of developing breast cancer and calculating the associated cancer risk. This review discusses the current genetic mutations conferring risk of developing breast cancer and the management pathway for these women with identifiable mutations as well as those with a strong family...
Topics
- Adult
- Age Factors
- Aged
- Breast Neoplasms
- Chemoprevention
- Early Detection of Cancer
- Female
- Genetic Predisposition to Disease
- Genetic Testing
- Health Behavior
- Humans