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Article

Dissecting the phyloepidemiology of Trypanosoma cruzi I (TcI) in Brazil by the use of high resolution genetic markers.

PLoS neglected tropical diseases - 1 May 2018

Roman Fabiola, das Chagas Xavier Samanta, Messenger Louisa A, Pavan Márcio G, Miles Michael A, Jansen Ana María, Yeo Matthew

Abstract excerpt

BACKGROUND: Trypanosoma cruzi, the causal agent of Chagas disease, is monophyletic but genetically heterogeneous. It is currently represented by six genetic lineages (Discrete Typing Units, DTUs) designated TcI-TcVI. TcI is the most geographically widespread and genetically heterogeneous lineage, this as is evidenced by a wide range of genetic markers applied to isolates spanning a vast geographic range in Latin...

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PMID: 29782493
DOI: 10.1371/journal.pntd.0006466
PMCID: PMC5983858

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Source receipt: pubmed, retrieved 7 Sept 2026.

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