Article

Strain-specific genome evolution in <i>Trypanosoma cruzi</i> , the agent of Chagas disease

2020-07-15

Abstract excerpt

The protozoan Trypanosoma cruzi almost invariably establishes life-long infections in humans and other mammals, despite the development of potent host immune responses that constrain parasite numbers. The consistent, decades-long persistence of T. cruzi in human hosts arises at least in part from the remarkable level of genetic diversity in multiple families of genes encoding the primary target antigens of anti-...

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Literature Corpus work: f7e0eec2-4525-5fbe-a3ef-96085406e014
DOI: 10.1101/2020.07.15.204479

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