Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolic Profiling of Epigenetic Aging and Its Associations With Aging-Related Phenotypes and Modifiable Lifestyle Factors.

Aging cell - 1 Sept 2026

Zhao Xunying, Ma Tianpei, Xia Maoyao, Dui Xinyang, Zhong Yangdan, Chen Xin, Qu Yang, Lei Bowen, Zhao Qingwen, Wu Xueyao, Yan Haiyu, Zhang Xingyu, Jiang Ke, Hu Lin, Long Lu, Fan Mengyu, Liao Jiaqiang, Zhang Tao, Jiang Xia, Li Jiayuan, Zhang Ben

Abstract excerpt

Epigenetic aging biomarkers are well-established hallmarks of biological aging, yet their metabolic underpinnings remain largely unexplored. Here, we characterized metabolic signatures associated with five epigenetic aging biomarkers (HorvathAge, HannumAge, DNAmPhenoAge, DunedinPACE, and DNAmTL) and examined their clinical relevance and potential determinants in 7162 Chinese older adults from two cohorts (primary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers

Share to Epigenesis, Genetic

Share to Life Style

Share to Metabolome

Share to Metabolomics

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 42634388
DOI: 10.1111/acel.70657
PMCID: PMC13501003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolic Profiling of Epigenetic Aging and Its Associations With Aging-Related Phenotypes and Modifiable Lifestyle Factors.PMID 42634388Read ↗

Heterogeneous metabolomic aging across the same age and prediction of health outcomeSemantic proximity Read ↗

Epigenetic and Metabolomic Biomarkers for Biological Age: A Comparative Analysis of Mortality and Frailty RiskSemantic proximity Read ↗

Evaluation of epigenetic and metabolomic biomarkers indicating biological ageSemantic proximity Read ↗

Metabolomic and lifestyle profiles refine BMI-metabolic phenotypes in older adults.Semantic proximity Read ↗

Epigenetic age acceleration links atherogenic dyslipidaemia, inflammageing and frailty with adverse cardiovascular outcomes in older adults (UFO): a lipid-metabolome and epigenetic clock analysisSemantic proximity Read ↗

OMICmAge: An integrative multi-omics approach to quantify biological age with electronic medical recordsSemantic proximity Read ↗

Quantitative Insights into Common and Organ-Specific Aging Gaps via Integrated Multi-Omics AnalysisSemantic proximity Read ↗

Implications of metabolism on multi‐systems healthy aging across the lifespanSemantic proximity Read ↗

Association of metabolomic aging acceleration and body mass index phenotypes with mortality and obesity-related morbidities.Semantic proximity Read ↗

Nonlinear dynamics of multi-omics profiles during human agingSemantic proximity Read ↗

Accelerated Epigenetic Aging Is Associated With Multiple Cardiometabolic, Hematologic, and Renal Abnormalities: A Project Baseline Health SubstudySemantic proximity Read ↗

Accelerated biological aging, genetic susceptibility, and incident severe MASLD, liver cirrhosis and cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.