Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolomic and lifestyle profiles refine BMI-metabolic phenotypes in older adults.

Cell reports. Medicine - 21 Jul 2026

Chen Yifan, Huang Honghao, Xu Wei, Zhang Wei, Wang Yuehong, Cao Linlin, Zhao Hang, Zhang Ziyue, Xu Yudian, Yuan Ancai, Hu Liuhua, Jiang Huiru, Hou Xiaowen, Schunkert Heribert, Ji John S, Qian Kun, Pu Jun

Abstract excerpt

Conventional BMI-based classifications, even when combined with traditional cardiometabolic risk factors, limit precision in aging-related risk assessment. Here, we perform metabolomic analysis in 13,202 older adults from the natural aging cohort (NCT04517513). Leveraging a panel of 39 core metabolites, we develop accurate and interpretable machine learning models to identify metabolic dysfunction across...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Life Style

Share to Metabolome

Share to Metabolomics

Share to Obesity

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 42385710
DOI: 10.1016/j.xcrm.2026.102907
PMCID: PMC13400187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolomic and lifestyle profiles refine BMI-metabolic phenotypes in older adults.PMID 42385710Read ↗

Heterogeneous metabolomic aging across the same age and prediction of health outcomeSemantic proximity Read ↗

Implications of metabolism on multi‐systems healthy aging across the lifespanSemantic proximity Read ↗

Association of metabolomic aging acceleration and body mass index phenotypes with mortality and obesity-related morbidities.Semantic proximity Read ↗

Decoding heterogeneous aging clocks and disease risk stratification using a metabolomic foundation modelSemantic proximity Read ↗

Metabolomic epidemiology offers insights into disease aetiology.Semantic proximity Read ↗

Multi-organ metabolome biological age implicates cardiometabolic conditions and mortality riskSemantic proximity Read ↗

Multi-organ metabolome biological age implicates cardiometabolic conditions and mortality risk.Semantic proximity Read ↗

Metabolic Profiling of Epigenetic Aging and Its Associations With Aging-Related Phenotypes and Modifiable Lifestyle Factors.Semantic proximity Read ↗

Cardiovascular risk of metabolically healthy obesity in two european populations: Prevention potential from a metabolomic study.Semantic proximity Read ↗

NMR metabolomic modelling of age and lifespan: a multi-cohort analysisSemantic proximity Read ↗

Metabolomic and genomic prediction of common diseases in 477,706 participants in three national biobanksSemantic proximity Read ↗

Whole Blood Metabolomics in Aging ResearchSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.