Metabolomic profiling of telomere length: associations with aging-related phenotypes and modifiable lifestyle factors in Chinese older adults.

doi:10.1093/gerona/glag209

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Article

Metabolomic profiling of telomere length: associations with aging-related phenotypes and modifiable lifestyle factors in Chinese older adults.

The journals of gerontology. Series A, Biological sciences and medical sciences - 5 Sept 2026

Ma Tianpei, Zhao Xunying, Jiang Ke, Lin Lei, Xu Lanjin, Yang Nan, Chen Xin, Zhao Qingwen, Zhang Xingyu, Yan Haiyu, Dui Xinyang, Xiao Jinyu, Fan Mengyu, Long Lu, Liao Jiaqiang, Zhang Tao, Jiang Xia, Li Jiayuan

Abstract excerpt

BACKGROUND: Telomere length (TL) is a well-established biomarker of cellular senescence, yet the metabolic profile of TL and its associations with aging-related phenotypes and responses to modifiable lifestyle factors remain unclear. METHODS: TL was measured using quantitative real-time polymerase chain reaction (qPCR) in 282 participants from the West China Health and Aging Cohort (WCHAC). Plasma metabolites...

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Topics

Humans
Female
Aged
Male
Phenotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Life Style

Metabolomics

China

Aging

Telomere

Biomarkers

Telomere Homeostasis

Middle Aged

Cellular Senescence

East Asian People

Source

Open in PubMed

Identifiers

PMID: 42663576
DOI: 10.1093/gerona/glag209

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