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Article

G protein-coupled estrogen receptor (GPER) modulates epithelial-mesenchymal transition-like phenotype in human glioblastoma cells.

Cell adhesion & migration - 31 Dec 2026

Peña-Gutiérrez Karla Mariana, Hernández-Ortega Karina, Castro-Reyes Beatriz Arantxa, Rosas-Benitez Andrea, Vázquez-Martínez Edgar Ricardo, García-Becerra Rocío, Camacho-Arroyo Ignacio

Abstract excerpt

Glioblastomas (GBs) are the most frequent and aggressive central nervous system tumors, whose progression is influenced by sex hormones. 17β-estradiol (E2), promotes an epithelial-to-mesenchymal transition (EMT)-like process and enhances proliferative, migratory, and invasive capacities in GB through intracellular estrogen receptors. However, the role of G protein-coupled estrogen receptor (GPER) in GB remains...

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Identifiers

PMID: 42626999
DOI: 10.1080/19336918.2026.2720325
PMCID: PMC13502043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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